Real Madrid thrashed Liverpool 2-5 in the first leg of their Round of 16 Champions League match at Anfield
The Los Blancos are heavy favorites to qualify, and the Reds will need more than a miracle at the Bernabeu to make the last eight.
Jurgen Klopp has dealt with numerous injury issues this season, and the German manager has suffered yet another blow.
Captain Jordan Henderson and youngster Stefan Bajcetic are both expected to miss the clash against the defending European champions.
In such a case, veteran James Milner is likely to start in central midfield alongside Fabinho and Harvey Elliott.
Joe Gomez has returned to training, and Matip is available, but Konate and Van Dijk will likely keep their central defensive roles in front of Brazilian shot stopper Alisson Becker.
Trent Alexander-Arnold and Andrew Robertson would almost certainly return to the fullback positions.
In the attack, Roberto Firmino could start with Mohamed Salah and Darwin Nunez, replacing winter addition Cody Gakpo.
Liverpool’s anticipated 4-3-3 XI vs Real Madrid is as follows: